Director: Yakov Goldstein
Address: 16/10, Mikluho-Maklaya Street, 117997 Moscow, Russian Federation
Going to a hospital, the last thing you want to think about is getting infected. Unfortunately, the problem of Healthcare Associated Infections (HAI) is growing ever more acute. Here are only a couple of facts to see the scale of the problem:
- The official US statistics (According to the CDC) counts over 2 million cases of nosocomial infections, over 100 thousand of them with lethal outcome. The financial loss by various estimates exceeds 30 billion US dollars.
- The research in the US shows that over 28% of bacteria and microorganisms being the source of nosocomial infections are resistant against all present day antibiotics.
- Multi-drug resistant pathogens and microorganisms are capable of surviving up to 2 months in hospital environment.
Healthcare Associated Infections mean increased time of hospital stay, mortality growth, financial and reputation loss, social and psychological damage.
However, there’s a way to save human lives and to protect patients and healthcare workers from HAIs. And this way is the unique technology of pulsed UV disinfection.
Research and development:
Over the years, our pulsed xenon UV technology
won numerous scientific and innovation awards, including 2010 Russian
Federation Government Prize in Science and Technology for developing and
implementing the pulsed plasma-optical technology in space medicine. Modified
pulsed xenon units are currently used to disinfect all cargo moving to the international space station.
The main operating principle of the Yanex units is very simple: The air and open surfaces are exposed to pulsed high-intensity light of continuous spectrum with the frequency of 2 to 5 flashes per second. Famously the ultraviolet irradiation can be divided into three spectra: UV-A, UV-B and UV-C. The former two types are common for us while UV-C does not penetrate the Earth atmosphere, which means the microorganisms have no protection against it.
The ultraviolet light of this wavelength penetrates the cell walls of bacteria, viruses and other microorganisms directly destructing their DNA and inactivating them.
The irradiation in the 230-300 nm range causes primarily dimerization of nucleic acids (mostly thymine dimers are formed).
The ultraviolet light with a wavelength shorter than 230 nm causes a number of destructive processes, namely:
- lipids photooxidation leads to depression of membrane barrier functions;
- photohydration of the DNA pyrimidine bases, formation of intermolecular cross-links (DNA - DNA, DNA - protein, protein - protein), single- or even double-strand breaks of DNA ensure the irreversible microorganisms inactivation;
- destruction of amino-acid residues in enzymes, protein photoinactivation and photodegradation of various coenzymes drop the activity of repair processes in the cell.
The source of ultraviolet light in Yanex units is a xenon lamp. A powerful electric discharge in the gas (xenon) inside a quartz bulb generates plasma emitting a light flash spectrally very similar to the Sun. Further still, the xenon plasma brightness (7500 - 9500°K) is higher than the Sun’s (5600°K).
The disinfection efficacy depends on the germicidal dose calculated by the unit automatically with regard to the following:
- size of the treated room;
- required germicidal efficiency.
The operator using a control panel
inputs these parameters, after that the unit starts the disinfection
cycle. A built-in bactericidal flow indicator constantly analyzes the
lamp operation and turns off the unit upon reaching the required
germicidal dose. This practice significantly increases the quality and
reliability of decontamination. UV-irradiation has been used for
disinfection purposes for quite a long time already.
Products and services:
Pulsed UV units of “Yanex” series are highly effective for fast air and surfaces disinfection from various microorganisms, including multi-resistant hospital strains (MRSA, VRE, M. tuberculosis, P. aerugenosa).
Currently, over 2000 units are operating at more than 400 healthcare facilities in Russia, USA, Mexico, Canada, Israel and other countries.